Trial intelligence / Profile preview

Phase I dose-escalation study of RO6958688 in CEA-positive advanced solid tumors

NL-OMON46944Phase 1Active, not recruiting

Sponsor
Roche
Start
Feb 2015
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 1, open-label trial of cibisatamab in Nonhematologic neoplasms, gastrointestinal cancer, colorectal cancer (CRC) and 2 more (2 arms), sponsored by Roche. Primary endpoints: Safety profile, Maximum tolerated dose and recommended dose/schedule and 3 more. Started Feb 2015; status: active, not recruiting.

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Drugs

cibisatamab
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Conditions

Nonhematologic neoplasmsgastrointestinal cancercolorectal cancer (CRC)non-small cell lung cancer (NSCLC)breast cancer

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