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COWBOY phase 2 trial of vemurafenib + cobimetinib induction before ipilimumab + nivolumab in BRAF V600-mutant melanoma with elevated LDH

NL-OMON46997Phase 2Recruiting

Sponsor
Radboud University Medical Center
Start
Feb 2017
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of vemurafenib, cobimetinib, ipilimumab and nivolumab in melanoma (2 arms), sponsored by Radboud University Medical Center. Primary endpoint: Best overall response rate. Started Feb 2017; status: recruiting.

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Drugs

vemurafenibcobimetinibipilimumabnivolumab
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Conditions

melanoma

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