Trial intelligence / Profile preview

RTH258 versus aflibercept in neovascular age-related macular degeneration

NL-OMON47226Phase 3Active, not recruiting

Sponsor
Novartis
Start
Nov 2015
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Engineered Antibody Formats → Antibody-Based Therapeutics, scFv Fragments → Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised, double-blind trial in exudative macular degeneration comparing RTH258 6 mg with Aflibercept 2 mg (2 arms). Primary endpoint: Change in best-corrected visual acuity from baseline to Week 48. Started Nov 2015; status: active, not recruiting.

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Drugs

brolucizumabaflibercept
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Conditions

exudative macular degeneration

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