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PK-guided conversion from Advagraf to Envarsus in stable liver transplant recipients
NL-OMON47419Active, not recruiting
- Sponsor
- Leiden University Medical Center
- Start
- Sep 2017
- Modality
- RNA-Targeting Small Molecules → Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Open-label, single-arm trial of tacrolimus in liver transplant, sponsored by Leiden University Medical Center. Primary endpoints: Population pharmacokinetic parameters of tacrolimus (Envarsus) and Pharmacokinetic dependency on CYP3A5*3, CYP3A4*22 and interleukin genotypes. Started Sep 2017; status: active, not recruiting.
02
Drugs
tacrolimus
03
Conditions
liver transplant
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