Trial intelligence / Profile preview

Nivolumab and nivolumab + ipilimumab in virus-associated and virus-negative solid tumors

NL-OMON47503Phase 2Active, not recruiting

Sponsor
Bristol Myers Squibb
Start
Nov 2015
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of nivolumab and ipilimumab in head and neck squamous cell carcinoma (HNSCC), Merkel cell carcinoma (MCC), nasopharyngeal carcinoma (NPC) and 5 more (3 cohorts), sponsored by Bristol Myers Squibb. Primary endpoints: Safety and tolerability in neoadjuvant cohort and Objective response rate in metastatic/recurrent cohort. Started Nov 2015; status: active, not recruiting.

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Drugs

nivolumabipilimumab
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Conditions

head and neck squamous cell carcinoma (HNSCC)Merkel cell carcinoma (MCC)nasopharyngeal carcinoma (NPC)cervical squamous cell carcinoma (CSCC)vaginal squamous cell carcinoma (SCCV)

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