Trial intelligence / Profile preview

MEDI0680 + durvalumab versus nivolumab in advanced clear-cell renal cell carcinoma

NL-OMON47649Phase 2Active, not recruiting

Sponsor
AstraZeneca
Start
Mar 2018
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, randomised, open-label trial in clear cell renal cell carcinoma (ccRCC) and kidney cancer comparing MEDI0680 + durvalumab, nivolumab monotherapy and MEDI0680 monotherapy (3 arms). Primary endpoint: Objective response. Started Mar 2018; status: active, not recruiting.

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Drugs

MEDI0680durvalumabnivolumab
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Conditions

clear cell renal cell carcinoma (ccRCC)kidney cancer

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