Trial intelligence / Profile preview

VX-445 triple-combination study in adults with cystic fibrosis

NL-OMON47700Phase 2Active, not recruiting

Sponsor
Vertex Pharmaceuticals
Start
Oct 2017
Modality
Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of elexacaftor, tezacaftor, ivacaftor and deutivacaftor in cystic fibrosis (CF) (4 arms), sponsored by Vertex Pharmaceuticals. Primary endpoints: Safety and tolerability, Absolute change in ppFEV1 and 2 more. Started Oct 2017; status: active, not recruiting.

02

Drugs

elexacaftortezacaftorivacaftordeutivacaftor
03

Conditions

cystic fibrosis (CF)

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