Trial intelligence / Profile preview

Atezolizumab with carboplatin + paclitaxel with or without bevacizumab versus carboplatin + paclitaxel + bevacizumab in first-line stage IV non-squamous NSCLC

NL-OMON47780Phase 3Active, not recruiting

Sponsor
Roche
Start
Mar 2016
Modality
DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial in non-small cell lung cancer (NSCLC) comparing Atezolizumab + carboplatin + paclitaxel, Atezolizumab + carboplatin + paclitaxel + bevacizumab and Carboplatin + paclitaxel + bevacizumab (3 arms). Primary endpoints: Progression-free survival and Overall survival. Started Mar 2016; status: active, not recruiting.

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Drugs

atezolizumabcarboplatinpaclitaxelbevacizumab
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Conditions

non-small cell lung cancer (NSCLC)

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