Trial intelligence / Profile preview

Phase I study of GSK3174998 alone and with pembrolizumab in advanced solid tumors

NL-OMON47867Phase 1Active, not recruiting

Sponsor
GSK
Start
Sep 2015
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of gsk3174998 and pembrolizumab in Nonhematologic neoplasms, non-small cell lung cancer (NSCLC), head and neck squamous cell carcinoma (HNSCC) and 6 more (2 arms), sponsored by GSK. Primary endpoints: Safety and tolerability and Maximum tolerated dose or maximum administered dose. Started Sep 2015; status: active, not recruiting.

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Drugs

gsk3174998pembrolizumab
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Conditions

Nonhematologic neoplasmsnon-small cell lung cancer (NSCLC)head and neck squamous cell carcinoma (HNSCC)renal cell carcinoma (RCC)melanoma

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