Trial intelligence / Profile preview

ETHANASH trial of microbial ethanol in NASH

NL-OMON48065Active, not recruiting

Sponsor
Amsterdam University Medical Center
Start
May 2019
Modality
Small Molecules, Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Open-label trial of fomepizole, clindamycin, metronidazole and ciprofloxacin in metabolic dysfunction-associated steatohepatitis (MASH) and metabolic dysfunction-associated steatotic liver disease (MASLD) (2 cohorts), sponsored by Amsterdam University Medical Center. Primary endpoints: Peripheral plasma ethanol concentration during mixed meal test with and without fomepizole, Hepatic steatosis by liver ultrasonography and 6 more. Started May 2019; status: active, not recruiting.

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Drugs

fomepizoleclindamycinmetronidazoleciprofloxacin
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Conditions

metabolic dysfunction-associated steatohepatitis (MASH)metabolic dysfunction-associated steatotic liver disease (MASLD)

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