Trial intelligence / Profile preview

COWBOY trial of targeted induction before ipilimumab + nivolumab in BRAF V600-mutant melanoma with elevated LDH

NL-OMON48120Phase 2Active, not recruiting

Sponsor
Radboud University Medical Center
Start
Feb 2017
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of vemurafenib, cobimetinib, ipilimumab and nivolumab in melanoma and cutaneous malignancy (2 arms), sponsored by Radboud University Medical Center. Primary endpoint: Best overall response rate. Started Feb 2017; status: active, not recruiting.

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Drugs

vemurafenibcobimetinibipilimumabnivolumab
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Conditions

melanomacutaneous malignancy

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