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TRPV1, TRPA1 and TRPM3 agonist responses in human dermal arteries from normotensive and preeclamptic pregnancies
NL-OMON48401Recruiting
- Sponsor
- Erasmus MC
- Start
- Jul 2020
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Open-label trial of capsaicin, cinnamaldehyde, pregnenolone sulphate and CIM0216 in preeclampsia (2 cohorts), sponsored by Erasmus MC. Primary endpoints: Agonist-induced vascular contraction and relaxation, Antagonist inhibition of vascular responses and 2 more. Started Jul 2020; status: recruiting.
02
Drugs
capsaicincinnamaldehydepregnenolone sulphateCIM0216
03
Conditions
preeclampsia
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