Trial intelligence / Profile preview

First-in-human study of CX-2009 in advanced solid tumors

NL-OMON48575Phase 2Completed

Sponsor
CytomX Therapeutics, Inc.
Start
Oct 2018
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of praluzatamab ravtansine and pacmilimab in Nonhematologic neoplasms, breast cancer, prostate cancer (PCa) and 5 more (9 arms), sponsored by CytomX Therapeutics, Inc. Primary endpoints: Safety profile, Maximum tolerated dose / recommended Phase 2 dose and 7 more. Started Oct 2018; status: completed.

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Drugs

praluzatamab ravtansinepacmilimab
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Conditions

Nonhematologic neoplasmsbreast cancerprostate cancer (PCa)non-small cell lung cancer (NSCLC)epithelial ovarian cancer (EOC)

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