Trial intelligence / Profile preview

CB-103 first-in-human dose-escalation and expansion study in advanced NOTCH-altered cancers

NL-OMON48760Phase 1Withdrawn

Sponsor
Cellestia Biotech
Start
Jul 2017
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of limantrafin in Nonhematologic neoplasms, hematopoietic malignancies, breast cancer and 18 more (2 arms), sponsored by Cellestia Biotech. Primary endpoints: Maximum tolerated dose or recommended Phase II dose and Preliminary antitumor activity. Planned start Jul 2017; status: withdrawn.

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Drugs

limantrafin
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Conditions

Nonhematologic neoplasmshematopoietic malignanciesbreast cancercolorectal cancer (CRC)cholangiocarcinoma (CCA)

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