Trial intelligence / Profile preview

ABBV-368 combination therapy study in recurrent/metastatic head and neck squamous cell carcinoma

NL-OMON49382Phase 1Active, not recruiting

Sponsor
AbbVie Inc.
Start
Jun 2021
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of revdofilimab, tilsotolimod, paclitaxel and budigalimab in head and neck squamous cell carcinoma (HNSCC) (3 arms), sponsored by AbbVie Inc. Primary endpoints: Safety and tolerability, Pharmacokinetics of ABBV-368, tilsotolimod, and budigalimab and 1 more. Started Jun 2021; status: active, not recruiting.

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Drugs

revdofilimabtilsotolimodpaclitaxelbudigalimab
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Conditions

head and neck squamous cell carcinoma (HNSCC)

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