Trial intelligence / Profile preview

Generation Program prevention study of CAD106 or CNP520 in cognitively unimpaired APOE4 homozygotes at risk for Alzheimer's disease

NL-OMON50176Phase 2Active, not recruiting

Sponsor
Novartis
Start
Feb 2018
Modality
Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Recombinant Protein Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Peptide-based Cancer Vaccines → Cancer Vaccines → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Countries
1
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Overview

Phase 2, randomised, double-blind trial of amilomotide and umibecestat in Alzheimer's disease (AD) (4 arms), sponsored by Novartis. Primary endpoints: Time-to-event and Alzheimer's Prevention Initiative Preclinical Composite Cognitive test score. Started Feb 2018; status: active, not recruiting.

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Drugs

amilomotideumibecestat
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Conditions

Alzheimer's disease (AD)

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