Trial intelligence / Profile preview

DESTINY-Lung03

NL-OMON50973Phase 1Not yet recruiting

Sponsor
AstraZeneca
Start
Feb 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 1, open-label trial of trastuzumab deruxtecan, durvalumab, cisplatin, carboplatin and pemetrexed in non-small cell lung cancer (NSCLC) (8 arms), sponsored by AstraZeneca. Primary endpoint: Safety, tolerability, and RP2D determination. Planned start Feb 2021; status: not yet recruiting.

02

Drugs

trastuzumab deruxtecandurvalumabcisplatincarboplatinpemetrexed
03

Conditions

non-small cell lung cancer (NSCLC)

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