Trial intelligence / Profile preview

Obicetrapib in early Alzheimer's disease in APOE4 carriers

NL-OMON51159Phase 2Completed

Sponsor
NewAmsterdam Pharma
Start
Jan 2022
Modality
Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of obicetrapib in Alzheimer's disease (AD), sponsored by NewAmsterdam Pharma. Primary endpoint: Change from baseline in CSF and plasma ApoA-I, ApoE, small HDL particles, and ABCA1-driven cholesterol efflux in CSF at Day 168. Started Jan 2022; status: completed.

02

Drugs

obicetrapib
03

Conditions

Alzheimer's disease (AD)

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