Trial intelligence / Profile preview

Follow that CAR! Dutch prospective cohort of CAR T-cell therapy referral and treatment for B-cell malignancies

NL-OMON51188Recruiting

Sponsor
Amsterdam University Medical Center
Start
Jul 2022
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Small Molecules
Countries
1
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Overview

Open-label trial of itacitinib + axicabtagene ciloleucel in B-cell malignancy, diffuse large B-cell lymphoma (DLBCL), acute lymphoblastic leukemia (ALL) and 1 more (2 cohorts), sponsored by Amsterdam University Medical Center. Primary endpoints: Tumor board referral and eligibility assessment data, Overall survival and 18 more. Started Jul 2022; status: recruiting.

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Drugs

itacitinib + axicabtagene ciloleucel
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Conditions

B-cell malignancydiffuse large B-cell lymphoma (DLBCL)acute lymphoblastic leukemia (ALL)mantle cell lymphoma (MCL)

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