Trial intelligence / Profile preview

Open-label extension of AKCEA-APOCIII-LRX in familial chylomicronemia syndrome

NL-OMON51487Phase 3Recruiting

Sponsor
Ionis Pharmaceuticals
Start
Oct 2022
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 3, open-label, single-arm trial of olezarsen in primary chylomicronemia (FCS), sponsored by Ionis Pharmaceuticals. Primary endpoints: Platelet count decrease of at least 30%, Platelet count decrease of at least 50% and 11 more. Started Oct 2022; status: recruiting.

02

Drugs

olezarsen
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Conditions

primary chylomicronemia (FCS)

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