Trial intelligence / Profile preview

HER2CLIMB-02: tucatinib or placebo plus T-DM1 in advanced HER2-positive breast cancer

NL-OMON51919Phase 3Completed

Sponsor
Seagen Inc.
Start
Jul 2021
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial of tucatinib and trastuzumab emtansine in breast cancer (2 arms), sponsored by Seagen Inc. Primary endpoint: Progression-free survival by investigator assessment. Started Jul 2021; status: completed.

02

Drugs

tucatinibtrastuzumab emtansine
03

Conditions

breast cancer

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