Trial intelligence / Profile preview

RODEO patient-guided TKI dose reduction in chronic myeloid leukemia

NL-OMON52067Phase 4Recruiting

Sponsor
Radboud University Medical Center
Start
Jun 2022
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of imatinib, bosutinib, dasatinib, nilotinib and ponatinib in chronic myelogenous leukemia (CML), sponsored by Radboud University Medical Center. Primary endpoint: Intervention failure at 12 months after first dose reduction. Started Jun 2022; status: recruiting.

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Drugs

imatinibbosutinibdasatinibnilotinibponatinib
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Conditions

chronic myelogenous leukemia (CML)

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