Trial intelligence / Profile preview

DESTINY-Lung04 first-line trastuzumab deruxtecan versus platinum-pemetrexed-pembrolizumab in HER2-mutant advanced NSCLC

NL-OMON52083Phase 3Recruiting

Sponsor
AstraZeneca
Start
Mar 2022
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of trastuzumab deruxtecan in non-small cell lung cancer (NSCLC) (2 arms), sponsored by AstraZeneca. Primary endpoint: Progression-free survival by blinded independent central review. Started Mar 2022; status: recruiting.

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Drugs

trastuzumab deruxtecan
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Conditions

non-small cell lung cancer (NSCLC)

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