Trial intelligence / Profile preview

Crovalimab versus eculizumab in complement inhibitor-naive PNH

NL-OMON52285Phase 3Recruiting

Sponsor
Roche
Start
Nov 2021
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 3, randomised, open-label trial in paroxysmal nocturnal hemoglobinuria (PNH) comparing Crovalimab with Eculizumab (2 arms). Primary endpoints: Transfusion avoidance and Hemolysis control. Started Nov 2021; status: recruiting.

02

Drugs

crovalimabeculizumab
03

Conditions

paroxysmal nocturnal hemoglobinuria (PNH)

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