Trial intelligence / Profile preview

POTENTIA phase 1 trial of CB307 in PSMA-positive advanced or metastatic solid tumors

NL-OMON52294Phase 1Completed

Sponsor
Crescendo Biologics
Start
Oct 2021
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Gamma Emitters → Radiopharmaceuticals
Countries
1
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Overview

Phase 1, open-label, single-arm trial of 89Zr-CB307 in Nonhematologic neoplasms, prostate cancer (PCa), non-small cell lung cancer (NSCLC) and 4 more, sponsored by Crescendo Biologics. Primary endpoints: Dose-limiting toxicities and Safety and tolerability. Started Oct 2021; status: completed.

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Drugs

89Zr-CB307
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Conditions

Nonhematologic neoplasmsprostate cancer (PCa)non-small cell lung cancer (NSCLC)renal cell carcinoma (RCC)bladder cancer

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