Trial intelligence / Profile preview

CLL17 trial of ibrutinib versus venetoclax-based fixed-duration regimens in previously untreated CLL

NL-OMON52308Phase 3Recruiting

Sponsor
HOVON
Start
Mar 2021
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing Continuous ibrutinib monotherapy, Fixed-duration venetoclax + obinutuzumab and Fixed-duration ibrutinib + venetoclax (3 arms). Primary endpoint: Progression-free survival. Started Mar 2021; status: recruiting.

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Drugs

ibrutinibvenetoclaxobinutuzumab
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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