Trial intelligence / Profile preview

NASAM: Neoadjuvant and Adjuvant Encorafenib + Binimetinib for BRAF-mutant In-transit Melanoma Metastases

NL-OMON52356Phase 2Completed

Sponsor
Amsterdam University Medical Center
Start
Mar 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of encorafenib, binimetinib and nivolumab in cutaneous melanoma (CM) and melanoma, sponsored by Amsterdam University Medical Center. Primary endpoint: Pathologic response to neoadjuvant encorafenib + binimetinib. Started Mar 2022; status: completed.

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Drugs

encorafenibbinimetinibnivolumab
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Conditions

cutaneous melanoma (CM)melanoma

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