Trial intelligence / Profile preview

HSCT versus alemtuzumab, cladribine, or ocrelizumab for aggressive relapsing-remitting multiple sclerosis

NL-OMON52451Phase 3Recruiting

Sponsor
Helse Bergen
Start
Jan 2020
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial of cyclophosphamide, antithymocyte globulin rabbit, alemtuzumab, cladribine and ocrelizumab in multiple sclerosis (MS) (2 arms), sponsored by Helse Bergen. Primary endpoints: Proportion of patients with no evidence of disease activity during 96 weeks and Proportion of patients with no evidence of disease activity during 240 weeks. Started Jan 2020; status: recruiting.

02

Drugs

cyclophosphamideantithymocyte globulin rabbitalemtuzumabcladribineocrelizumab
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Conditions

multiple sclerosis (MS)

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