Trial intelligence / Profile preview

ZUMA-7: axicabtagene ciloleucel versus standard second-line care in relapsed or refractory large B-cell lymphoma

NL-OMON52520Phase 3Completed

Sponsor
Kite Pharma
Start
Jun 2018
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Countries
1
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Overview

Phase 3, randomised, open-label trial in diffuse large B-cell lymphoma (DLBCL), large-cell lymphoma, follicular lymphoma, transformed (t-FL) and 4 more comparing Axicabtagene ciloleucel arm with Standard of care arm (2 arms). Primary endpoint: Event-free survival. Started Jun 2018; status: completed.

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Drugs

axicabtagene ciloleucel
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Conditions

diffuse large B-cell lymphoma (DLBCL)large-cell lymphomafollicular lymphoma, transformed (t-FL)T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL)diffuse large B-cell lymphoma associated with chronic inflammation (DLBCL-CI)

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