Trial intelligence / Profile preview

DA-EPOCH-R induction followed by nivolumab consolidation for newly diagnosed double-hit/triple-hit high-grade B-cell lymphoma

NL-OMON52523Phase 2Recruiting

Sponsor
HOVON
Start
Aug 2018
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of nivolumab, rituximab, etoposide, prednisone, vincristine and 2 more in large-cell lymphoma and high-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH), sponsored by HOVON. Primary endpoint: 12-month disease-free survival. Started Aug 2018; status: recruiting.

02

Drugs

nivolumabrituximabetoposideprednisonevincristine
03

Conditions

large-cell lymphomahigh-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements (HGBL-DH/TH)

Beyond the preview

Go deeper on NL-OMON52523.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on NL-OMON52523.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call