Trial intelligence / Profile preview

Phase 3 neoadjuvant gemcitabine/cisplatin with or without nivolumab and BMS-986205 in muscle-invasive bladder cancer

NL-OMON52608Phase 3Recruiting

Sponsor
Bristol Myers Squibb
Start
Mar 2020
Modality
Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, double-blind trial of nivolumab, linrodostat, gemcitabine and cisplatin in muscle-invasive bladder cancer (MIBC) and transitional cell carcinoma of the bladder (TCC), sponsored by Bristol Myers Squibb. Primary endpoints: Pathologic complete response rate for Arm C versus Arm A, Event-free survival for Arm C versus Arm A and 2 more. Started Mar 2020; status: recruiting.

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Drugs

nivolumablinrodostatgemcitabinecisplatin
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Conditions

muscle-invasive bladder cancer (MIBC)transitional cell carcinoma of the bladder (TCC)

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