Trial intelligence / Profile preview

Neoadjuvant FOLFOXIRI plus chemoradiotherapy for high-risk locally advanced rectal cancer

NL-OMON52634Phase 2Recruiting

Sponsor
Catharina Ziekenhuis
Start
Nov 2021
Modality
Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of fluorouracil, folinic acid, oxaliplatin and irinotecan in rectal cancer, sponsored by Catharina Ziekenhuis. Primary endpoint: Complete pathological response or sustained clinical complete response at 1 year. Started Nov 2021; status: recruiting.

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Drugs

fluorouracilfolinic acidoxaliplatinirinotecan
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Conditions

rectal cancer

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