Trial intelligence / Profile preview

PHP with or without ipilimumab + nivolumab for metastatic uveal melanoma

NL-OMON52669Phase 2Recruiting

Sponsor
Leiden University Medical Center
Start
Dec 2019
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
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Overview

Phase 2, randomised, open-label trial in intraocular melanoma and eye melanoma comparing PHP alone with PHP + ipilimumab + nivolumab (2 arms). Primary endpoints: Safety and tolerability, Dose-limiting toxicities and 3 more. Started Dec 2019; status: recruiting.

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Drugs

ipilimumabnivolumabmelphalan
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Conditions

intraocular melanomaeye melanoma

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