Trial intelligence / Profile preview

Long-term follow-up of participants treated with lentiviral adoptive cell therapies

NL-OMON52738Phase 2Not yet recruiting

Sponsor
Adaptimmune Therapeutics
Start
Jan 2026
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, TCR-Engineered T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
1
01

Overview

Phase 2, open-label, single-arm trial of letetresgene autoleucel, GSK3845097 and NY-ESO-1/LAGE-1a TCR-engineered T cells in cancer, Nonhematologic neoplasms and non-small cell lung cancer (NSCLC), sponsored by Adaptimmune Therapeutics. Primary endpoint: Delayed adverse events. Planned start Jan 2026; status: not yet recruiting.

02

Drugs

letetresgene autoleucelGSK3845097NY-ESO-1/LAGE-1a TCR-engineered T cells
03

Conditions

cancerNonhematologic neoplasmsnon-small cell lung cancer (NSCLC)

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