Trial intelligence / Profile preview

SONIA trial in HR-positive/HER2-negative metastatic breast cancer

NL-OMON53036Phase 3Completed

Sponsor
Borstkanker Onderzoek Groep
Start
Nov 2017
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of palbociclib, ribociclib, abemaciclib, letrozole, anastrozole and 1 more in breast cancer (2 arms), sponsored by Borstkanker Onderzoek Groep. Primary endpoint: Progression-free survival after two lines of treatment. Started Nov 2017; status: completed.

02

Drugs

palbociclibribociclibabemaciclibletrozoleanastrozole
03

Conditions

breast cancer

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