Trial intelligence / Profile preview

Nivolumab + brentuximab vedotin response-adapted phase II trial in pediatric and young adult relapsed/refractory classic Hodgkin lymphoma

NL-OMON53072Phase 2Completed

Sponsor
Bristol Myers Squibb
Start
Aug 2017
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, open-label trial of nivolumab, brentuximab vedotin and bendamustine in classical Hodgkin lymphoma (cHL) (3 arms), sponsored by Bristol Myers Squibb. Primary endpoints: 3-year event-free survival in low-risk group and Complete metabolic response before HDCT/ASCT in standard-risk group. Started Aug 2017; status: completed.

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Drugs

nivolumabbrentuximab vedotinbendamustine
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Conditions

classical Hodgkin lymphoma (cHL)

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