Trial intelligence / Profile preview

NICHE trial in early-stage colon cancer

NL-OMON53138Phase 2Recruiting

Sponsor
Netherlands Cancer Institute
Start
Mar 2017
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of nivolumab, ipilimumab, celecoxib, adakitug and relatlimab in colon adenocarcinoma and colorectal cancer (CRC) (6 arms), sponsored by Netherlands Cancer Institute. Primary endpoints: Safety and feasibility and 3-year disease-free survival. Started Mar 2017; status: recruiting.

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Drugs

nivolumabipilimumabcelecoxibadakitugrelatlimab
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Conditions

colon adenocarcinomacolorectal cancer (CRC)

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