Trial intelligence / Profile preview

Phase 2 multi-arm study of quavonlimab/pembrolizumab and other pembrolizumab-based combinations versus pembrolizumab in MSI-H/dMMR stage IV colorectal cancer

NL-OMON53742Phase 2Recruiting

Sponsor
Merck & Co.
Start
Apr 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 2, randomised, open-label trial of quavonlimab, pembrolizumab, favezelimab, vibostolimab and mk-4830 in colorectal cancer (CRC) and colorectal adenocarcinoma, sponsored by Merck & Co. Primary endpoint: Objective response rate by blinded independent central review. Started Apr 2023; status: recruiting.

02

Drugs

quavonlimabpembrolizumabfavezelimabvibostolimabmk-4830
03

Conditions

colorectal cancer (CRC)colorectal adenocarcinoma

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