Trial intelligence / Profile preview

Phase I/II triplet therapy study of binimetinib, lapatinib, and vinorelbine in RAS-mutated metastatic colorectal cancer

NL-OMON54073Phase 2Recruiting

Sponsor
University Medical Center Utrecht
Start
Aug 2020
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of binimetinib, lapatinib and vinorelbine in colorectal cancer (CRC) and metastatic colorectal adenocarcinoma (mCRC) (3 arms), sponsored by University Medical Center Utrecht. Primary endpoints: Dose-limiting toxicities leading to RP2D and Best overall response within 6 months. Started Aug 2020; status: recruiting.

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Drugs

binimetiniblapatinibvinorelbine
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Conditions

colorectal cancer (CRC)metastatic colorectal adenocarcinoma (mCRC)

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