Trial intelligence / Profile preview

Open-label extension of ISIS 721744 in hereditary angioedema

NL-OMON54255Phase 2Recruiting

Sponsor
Ionis Pharmaceuticals
Start
Nov 2020
Modality
Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, MicroRNA (miRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
01

Overview

Phase 2, open-label trial of donidalorsen in hereditary angioedema (HAE) (3 arms), sponsored by Ionis Pharmaceuticals. Primary endpoint: Incidence and severity of treatment-emergent adverse events. Started Nov 2020; status: recruiting.

02

Drugs

donidalorsen
03

Conditions

hereditary angioedema (HAE)

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