Trial intelligence / Profile preview

Amivantamab + lazertinib versus osimertinib versus lazertinib in first-line EGFR-mutated advanced NSCLC

NL-OMON54268Phase 3Recruiting

Sponsor
Janssen Pharmaceutical
Start
Oct 2021
Modality
Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing Amivantamab + lazertinib, Osimertinib and Lazertinib (3 arms). Primary endpoint: Progression-free survival. Started Oct 2021; status: recruiting.

02

Drugs

amivantamablazertinibosimertinib
03

Conditions

non-small cell lung cancer (NSCLC)

Beyond the preview

Go deeper on NL-OMON54268.

Study design, results and competitive context are available in the Gosset platform where reported.

Study design & results

Available in the Gosset platform where reported.

Competitive context

Available in the Gosset platform where reported.

Bring the full picture into focus.

See how Gosset can support your research on NL-OMON54268.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call