Trial intelligence / Profile preview

IMPAHCT trial of inhaled AV-101 in pulmonary arterial hypertension

NL-OMON54466Phase 2Not yet recruiting

Sponsor
Aerovate Therapeutics, Inc
Start
May 2023
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, randomised, double-blind trial of 4-chlorokynurenine in pulmonary arterial hypertension (PAH) (4 arms), sponsored by Aerovate Therapeutics, Inc. Primary endpoints: Placebo-corrected change from baseline in pulmonary vascular resistance at Week 24 and Placebo-corrected change from baseline in 6-minute walk distance at Week 24. Planned start May 2023; status: not yet recruiting.

02

Drugs

4-chlorokynurenine
03

Conditions

pulmonary arterial hypertension (PAH)

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