Trial intelligence / Profile preview

HOVON phase III trial of VMP versus HDM/ASCT with optional VRD consolidation in newly diagnosed multiple myeloma

NL-OMON54491Phase 3Completed

Sponsor
HOVON
Start
Jan 2011
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of bortezomib, melphalan, prednisone, lenalidomide, dexamethasone and 1 more in multiple myeloma (MM) (5 arms), sponsored by HOVON. Primary endpoints: Progression-free survival from registration, Progression-free survival from randomization R1 and 1 more. Started Jan 2011; status: completed.

02

Drugs

bortezomibmelphalanprednisonelenalidomidedexamethasone
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Conditions

multiple myeloma (MM)

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