Trial intelligence / Profile preview

Larotrectinib in pediatric patients with advanced solid or primary CNS tumors

NL-OMON54602Phase 2Recruiting

Sponsor
Bayer Consumer Health
Start
Jul 2019
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of larotrectinib in Nonhematologic neoplasms, central nervous system tumor, congenital fibrosarcoma (CFS) and 2 more (2 arms), sponsored by Bayer Consumer Health. Primary endpoints: Dose-limiting toxicity and Overall response rate. Started Jul 2019; status: recruiting.

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Drugs

larotrectinib
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Conditions

Nonhematologic neoplasmscentral nervous system tumorcongenital fibrosarcoma (CFS)mesoblastic nephroma (CMN)secretory breast carcinoma (SBC)

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