Trial intelligence / Profile preview

Gilteritinib versus midostaurin with intensive chemotherapy in newly diagnosed FLT3-mutated AML or MDS-EB2

NL-OMON54682Phase 3Active, not recruiting

Sponsor
HOVON
Start
Dec 2019
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) comparing Gilteritinib arm with Midostaurin arm (2 arms). Primary endpoint: Overall survival. Started Dec 2019; status: active, not recruiting.

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Drugs

gilteritinibmidostaurin
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Conditions

acute myeloid leukemia (AML)myelodysplastic syndrome (MDS)

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