Trial intelligence / Profile preview

Epcoritamab dose-escalation and expansion study in relapsed or refractory B-cell lymphoma

NL-OMON54761Phase 2Recruiting

Sponsor
Genmab
Start
Jul 2018
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 2, open-label trial of epcoritamab in mature B-cell lymphoma, non-Hodgkin lymphoma (NHL), diffuse large B-cell lymphoma (DLBCL) and 6 more (5 arms), sponsored by Genmab. Primary endpoints: Dose-limiting toxicity, Adverse events and 2 more. Started Jul 2018; status: recruiting.

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Drugs

epcoritamab
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Conditions

mature B-cell lymphomanon-Hodgkin lymphoma (NHL)diffuse large B-cell lymphoma (DLBCL)large-cell lymphomaprimary mediastinal large B-cell lymphoma (PMBCL)

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