Trial intelligence / Profile preview

AMG 160 combinations with enzalutamide or abiraterone in metastatic castration-resistant prostate cancer

NL-OMON54909Phase 1Withdrawn

Sponsor
Amgen
Start
Jul 2020
Modality
Small Molecules, T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 1, open-label trial of acapatamab, enzalutamide and abiraterone in metastatic castration-resistant prostate cancer (mCRPC) (2 arms), sponsored by Amgen. Primary endpoints: Dose-limiting toxicities, Treatment-emergent and treatment-related adverse events and 1 more. Planned start Jul 2020; status: withdrawn.

02

Drugs

acapatamabenzalutamideabiraterone
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Conditions

metastatic castration-resistant prostate cancer (mCRPC)

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