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DONIMI neoadjuvant domatinostat, nivolumab, and ipilimumab in stage III melanoma

NL-OMON54971Phase 1Completed

Sponsor
Netherlands Cancer Institute
Start
Jan 2020
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of Domatinostat, nivolumab and ipilimumab in melanoma, cutaneous melanoma (CM) and melanoma of unknown primary (MUP) (4 arms), sponsored by Netherlands Cancer Institute. Primary endpoints: Safety and feasibility and Pathologic response rate. Started Jan 2020; status: completed.

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Drugs

Domatinostatnivolumabipilimumab
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Conditions

melanomacutaneous melanoma (CM)melanoma of unknown primary (MUP)

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