Trial intelligence / Profile preview

ALLTogether1 for newly diagnosed acute lymphoblastic leukemia in children and young adults

NL-OMON55098Phase 3Recruiting

Sponsor
Karolinska University Hospital
Start
Jul 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of doxorubicin, vincristine, dexamethasone, inotuzumab ozogamicin, tioguanine and 2 more in acute lymphoblastic leukemia (ALL), B cell acute lymphoblastic leukemia (B-ALL) and Precursor T-cell lymphoblastic leukemia/lymphoma (T-LBL/ALL) (10 arms), sponsored by Karolinska University Hospital. Primary endpoints: Event-free survival, Disease-free survival and 1 more. Started Jul 2020; status: recruiting.

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Drugs

doxorubicinvincristinedexamethasoneinotuzumab ozogamicintioguanine
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Conditions

acute lymphoblastic leukemia (ALL)B cell acute lymphoblastic leukemia (B-ALL)Precursor T-cell lymphoblastic leukemia/lymphoma (T-LBL/ALL)

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