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Phase II randomized open-label study of LXH254 combination regimens in previously treated BRAF V600- or NRAS-mutant metastatic melanoma

NL-OMON55115Phase 2Active, not recruiting

Sponsor
Novartis
Start
Apr 2021
Modality
Small Molecules
Countries
1
01

Overview

Phase 2, randomised, open-label trial in melanoma comparing LXH254 + LTT462, LXH254 + trametinib and LXH254 + ribociclib (3 arms). Primary endpoint: Objective response rate. Started Apr 2021; status: active, not recruiting.

02

Drugs

naporafenibrineterkibtrametinibribociclib
03

Conditions

melanoma

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